Cox Model Setup May Lead to Erroneous Conclusions

Cox Model Setup May Lead to Erroneous Conclusions

Current Incentives for Scientists Lead to Underpowered Studies with Erroneous Conclusions

We can regard the wider incentive structures that operate across science, such as the priority given to novel findings, as an ecosystem within which scientists strive to maximise their fitness (i.e., publication record and career success). Here, we develop an optimality model that predicts the most rational research strategy, in terms of the proportion of research effort spent on seeking novel ...

Cox Model Setup: Garshick et al. Respond

Response to: Analyses Using Time-Dependent Pioglitazone Usage in Cox Models May Lead to Wrong Conclusions About Its Association With Cancer

W e thank Yang and Chan (1) for their interest in our articles (2,3). They propose that our studiesmay be biased by use of time-varying exposures in Cox regression models. If more severe hyperglycemia is associated both with increased cancer risk and with use of pioglitazone, and it is also affected by pioglitazone therapy (i.e., hyperglycemia is both a confounder and an intermediate variable),...

Teaching methods are erroneous: approaches which lead to erroneous end-user computing

If spreadsheets are not erroneous then who, or what, is? Research has found that end-users are. If end-users are erroneous then why they are? Research has found that responsibility lies with human beings’ fast and slow thinking modes and the inappropriate way they use them. If we are aware of this peculiarity of human thinking, then why do we not teach students how to train their brains? This i...